Expresión de búsqueda:
COMPLEMENT C1 INHIBITOR PROTEIN
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DeCS
Descriptor
Inglés
:
Complement C1 Inhibitor Protein
Descriptor
Español
:
Proteína Inhibidora del Complemento C1
Descriptor
Portugués
:
Proteína Inibidora do Complemento C1
Categoría:
D12.644.861.140.500
D12.776.124.486.274.920.250.500
D12.776.395.320
D12.776.872.140.500
Definición
Inglés
:
An endogenous 105-kDa
plasma
glycoprotein produced primarily by the LIVER and
MONOCYTES
. It inhibits a broad spectrum of proteases, including the
COMPLEMENT C1R
and the
COMPLEMENT C1S
proteases of the
CLASSICAL COMPLEMENT PATHWAY
, and the
MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES
. C1-INH-deficient individuals suffer from
HEREDITARY ANGIOEDEMA TYPES I AND II
.
Nota de Indización
Inglés
:
do not confuse with
COMPLEMENT C1 INACTIVATOR PROTEINS
Acción Farmacológica:
Complement Inactivating Agents
Combinados
Inglés
:
Complement C1 Inhibitor Protein
/
deficiency
use
Hereditary Angioedema Types I and II
Nota Histórica
Inglés
:
2006; for C1 ESTERASE INHIBITOR use COMPLEMENT C1 INACTIVATOR PROTEINS
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
50836
Identificador Único:
D050718
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS